Helicobacter pylori and Its Antibiotic Heteroresistance: A Neglected Issue in Published Guidelines
نویسندگان
چکیده
منابع مشابه
Antibiotic susceptibility, heteroresistance, and updated treatment strategies in Helicobacter pylori infection
In this review, we discuss the problem of antibiotic resistance, heteroresistance, the utility of cultures and antibiotic susceptibility tests in Helicobacter pylori (Hp) eradication, as well as the updated treatment strategies for this infection. The prevalence of antibiotic resistance is increasing all over the world, especially for metronidazole and clarithromycin, because of their heavy use...
متن کاملAntibiotic susceptibilities of Helicobacter pylori.
OBJECTIVE The aim of this study was to evaluate the prevalence of resistance among 83 Helicobacter pylori isolates cultured from biopsies taken during routine endoscopies in 1998-1999. METHODS Minimum Inhibitory Concentration of amoxicillin, tetracycline, clarithromycin and metronidazole were determined by Epsilometer test. RESULTS Forty-seven strains (57%) were resistant to metronidazole, ...
متن کاملAntibiotic resistance in Helicobacter pylori infection.
Resistance to antibiotics is considered as the primary reason for failure of eradication therapies. Resistance to clarithromycin is due to a decrease in binding to the ribosomes associated with a point mutation on the 23S rRNA. Its rate in Europe varies from 0-15%, with 5% in the UK. The resistance influences dramatically the success of the treatments. Resistance to metronidazole is due to a la...
متن کاملHelicobacter pylori in Iran: A systematic review on the antibiotic resistance
Objective(s):Helicobacter pylori (H. pylori) is a pathogenic bacterium that colonizes the stomachs of approximately 50% of the world’s population. Resistance of H. pylori to antibiotics is considered as the main reason for the failure to eradicate this bacterium. The aim of this study was to determine the rate of resistant H. pylori strains to various antimicrobial agents in different areas of ...
متن کاملAntibiotic Resistance in Helicobacter pylori Strains and its Effect on H. pylori Eradication Rates in a Single Center in Korea
BACKGROUND Clarithromycin, amoxicillin, metronidazole, tetracycline, and levofloxacin have been commonly used for the eradication of Helicobacter pylori. We compared the change in antibiotic resistance of H. pylori strains during two separate periods and investigated the effect of antibiotic resistance on H. pylori eradication. METHODS H. pylori strains were isolated from 71 patients between ...
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ژورنال
عنوان ژورنال: Frontiers in Microbiology
سال: 2019
ISSN: 1664-302X
DOI: 10.3389/fmicb.2019.01796